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The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health

The Hormone Solution is a top-ranked women’s health podcast focused on perimenopause, menopause, hormone replacement therapy (HRT), weight gain, metabolism, thyroid health, and midlife transformation. Hosted by Certified Hormone Specialist Karen Martel, this show helps women in their 40s and 50s understand what’s really happening with their hormones — and what to do about it. If you’re struggling with perimenopause symptoms, menopause weight gain, estrogen dominance, low progesterone, testosterone decline, brain fog, poor sleep, thyroid dysfunction, or metabolic slowdown, this podcast breaks it down in a clear, practical, no-nonsense way. Each episode features:• Evidence-based hormone education• Expert interviews• Real-world HRT guidance• Midlife weight loss strategies• Thyroid and metabolic health insights With over 2.5 million downloads and ranked in the Top 30 on iTunes, The Hormone Solution is trusted by women worldwide who want real answers about bioidentical hormones, menopause treatment options, and midlife health.New episodes every Tuesday and Saturday.Take the free hormone quiz at karenmartel.com

Mar 28, 2026

Why are so many of us blindsided by anxiety, depression, rage, or even suicidal thoughts in midlife? And why are hormones so often left out of the conversation? I’m joined by the incredible Dr. Louise Newson, a UK-based GP and menopause specialist, to talk about something far too many women experience in...


Mar 24, 2026

Have you looked in the mirror lately and wondered, when did my skin change like this? In this episode, I’m joined by Debbi Barber (founder of Vitali Regenerative Skincare) and Dr. Jordan Plews (a stem cell scientist and co-founder of Xytogen Biotech) to unpack what’s really happening to our skin in midlife—and...


Mar 21, 2026

In this Hormone Hotline episode, I’m answering a powerful question about estrogen HRT, histamine intolerance, and mast cell activation during perimenopause and long COVID. Why do histamine flares explode when hormones start shifting? Is estrogen really the villain—or is something deeper driving the chaos?

I share...


Mar 17, 2026

Welcome to Quick Hits — where we bring you the most impactful moments from past episodes in under 15 minutes.

Today’s clip comes from one of our most replayed conversations.

Listen to the full episode here: